เงื่อนไขการค้นหา

ทักษะ:

Research, Compliance, Legal

ประเภทงาน:

งานประจำ

• Develop, supervise, and oversee testing in the areas of Microbiology and Biotechnology within the Research Laboratory and Services, ensuring accuracy and compliance with international standards and legal requirements. This is to support the needs of customers within the Innovation & Product Development Center, within SCGP, and external customers.
• Develop quality systems, conduct evaluations, and design new analysis and testing methods. Provide technical consultation to support research activities and respond to ...
• Assess employee risks and improve work processes in the microbiology and biotechnology laboratories to ensure safety in accordance with legal and relevant standard requirements.
• Job Description Manage and oversee testing/inspection operations in the scientific and technical/quality laboratory areas.
• Develop and maintain work systems to ensure smooth operations and testing accuracy to support SCGP customers.
• Supervise and manage routine and new test methods to ensure readiness and compliance.
• Oversee laboratory operations and provide test result reports.
• Prepare laboratory readiness for audits and customer visits.
• Monitor and maintain equipment efficiency to ensure availability and performance.
• Develop and maintain the laboratorys Quality Management System to meet required standards and customer expectations.
• Ensure laboratory staff are aligned with the scientific and technical/quality functions and operate according to SCGP requirements.
• Develop scientific and technical work systems and support operational changes.
• Review and recommend suitable methods for each type of test and business unit.
• Develop testing systems to comply with ISO/IEC 17025 and ISO 13485 (as applicable).
• Maintain and update documents required by ISO/IEC 17025.
• Manage and monitor annual testing, equipment maintenance, and calibration plans.
• Prepare laboratory operational plans.
• Prepare annual and medium-term plans.
• Maintain and develop ISO/IEC 17025 systems in the laboratory.
• Manage laboratory cost structure and support scientific/technical data for Innovation and Product Development Centers (IPDC) to comply with SCG Safety Framework.
• Perform other duties as assigned.
• QualificationBachelor's/Master's degree in Medical Technology, Health Sciences, or related fields (Bachelor's G.P.A. > 2.70, Master's G.P.A. > 3.30).
• Open for New Graduates.
• Experience in QA/QC lab testing in the food and healthcare industry is an advantage.
• Knowledge in Microbiology and Biotechnology.
• Knowledge in Standards or Compliance related to labolatory or healthcare (ISO/IEC 17025, ISO 13485).
• Good command in English (TOEIC score at least 550).
• Must obtain a Professional License for Medical Technology issued by the Medical Technology Council.
• Able to work on-site mode at Innovation and Product Development Center (IPDC), SCGP, Ratchaburi, Thailand.
• Contact: Pupat (Mac) Email: [email protected]

ประสบการณ์:

2 ปีขึ้นไป

ทักษะ:

Biology, English

ประเภทงาน:

งานประจำ

• Accelerated Development: Our venture studio model streamlines the typically lengthy process of biotech innovation. With access to expert operational, legal, finance, and HR teams, you can bypass common startup hurdles and focus immediately on scientific advancement and strategic growth..
• Integrated Resource Access: You will have direct access to state-of-the-art labs, cutting-edge infrastructure, and specialized development and product teams tailored to your project s unique needs facilitating rapid iteration and optimized drug develop ...
• Collaborative Synergies: Joining our venture studio connects you with a vibrant ecosystem of experienced entrepreneurs, distinguished scientists, and industry leaders. This collaborative environment encourages cross-pollination of ideas, mentoring opportunities, and strategic partnerships, enhancing both innovation and your professional growth..
• Strategic Support and Investment: Beyond initial capital, Great Good provides ongoing strategic guidance and operational support. Our comprehensive back-office resources help manage day-to-day complexities while our investment in your venture ensures you have the means to scale quickly and capture market opportunities..
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• About the Role.
• We are seeking a motivated and experienced CRISPR Scientist to join our dynamic R&D team and drive the design, execution, and analysis of our gene editing projects. If you are passionate about translating innovative science into transformative medicine, we encourage you to apply..
• Design and execute experiments using various CRISPR-Cas systems (e.g., OPENCRISPR1, Cas9, Cas12a, Base Editors, Prime Editors) for gene editing in mammalian cells, including primary cells and immortalized cell lines. This scope of work is expected to include using machine learning platforms to screen, analyze, synthesize and test enzymes of the Cas and deaminase classes as well as nickase conversion..
• Develop and optimize methods for gRNA design, delivery (e.g., lipofectamine, lipid nanoparticles, electroporation), and assessment of editing efficiency and specificity using PCR and NGS technologies..
• Analyze and interpret complex data sets, including molecular biology assays (qPCR, Western Blot, ELISA), next-generation sequencing (NGS) data for on-target and off-target editing, and functional cell-based assays..
• Culture and manipulation of various cell lines (HEK-293, HeLa, iPSCs, and T cells), with a focus on validating utility of novel complexes to perform precise editing in cells..
• Troubleshoot experimental hurdles and contribute creative solutions to accelerate project timelines. This will include minimizing off-target and bystander editing by correct selection of PAMs and other critical sequences..
• Document experiments in electronic lab notebooks and present results clearly at internal meetings..
• Stay current with the latest scientific literature, technology advancements, and regulatory requirements pertaining to CRISPR and gene therapy..
• Collaborate effectively with interdisciplinary teams including technicians and scientists, in the immunology, cell biology, drug development and bioinformatics fields..
• Required.
• Ph.D. in Molecular Biology, Cell Biology, Genetics, Biochemistry, or a related field..
• Minimum of 2+ years of relevant post-doctoral or industry experience focused on gene editing techniques, specifically CRISPR technology. Experience in Base Editors and human T cells is desired..
• Deep expertise in mammalian cell culture techniques, including transfection and viral transduction..
• Proficiency in molecular biology techniques, including DNA/RNA isolation, PCR/qPCR, cloning, and gel electrophoresis..
• Demonstrated experience with assays used to quantify gene editing outcomes (e.g., T7 Endonuclease I assay, NGS library preparation and analysis)..
• Excellent written and verbal communication skills with the ability to present complex data effectively..
• Preferred.
• Industry experience in a Biotech or Pharmaceutical setting..
• Experience with non-Cas9 CRISPR systems (e.g., Base/Prime Editors, dCas9 fusions) is a strong plus..
• Familiarity with in vivo delivery methods and animal models..
• Experience with high-throughput screening and automation..
• Experience with CAR-T cell development.
• Experience with antiviral therapeutics..
• What We Offer.
• Competitive compensation and equity package in an early-stage, high-growth startup..
• The opportunity to make a significant impact on developing next-generation therapies..
• A collaborative, fast-paced, and intellectually stimulating culture..
• To Apply, please submit your CV and a cover letter detailing your relevant experience to [email protected] or Application Link: https://forms.gle/Ewgtmcgwuv6B5KJ66..