Filter Jobs

Experience:

2 years required

Skills:

Biology, English

Job type:

Full-time

• Accelerated Development: Our venture studio model streamlines the typically lengthy process of biotech innovation. With access to expert operational, legal, finance, and HR teams, you can bypass common startup hurdles and focus immediately on scientific advancement and strategic growth..
• Integrated Resource Access: You will have direct access to state-of-the-art labs, cutting-edge infrastructure, and specialized development and product teams tailored to your project s unique needs facilitating rapid iteration and optimized drug develop ...
• Collaborative Synergies: Joining our venture studio connects you with a vibrant ecosystem of experienced entrepreneurs, distinguished scientists, and industry leaders. This collaborative environment encourages cross-pollination of ideas, mentoring opportunities, and strategic partnerships, enhancing both innovation and your professional growth..
• Strategic Support and Investment: Beyond initial capital, Great Good provides ongoing strategic guidance and operational support. Our comprehensive back-office resources help manage day-to-day complexities while our investment in your venture ensures you have the means to scale quickly and capture market opportunities..
• Enhanced Commercial Potential: By working under the venture studio umbrella, you not only drive scientific breakthroughs but also elevate the commercial viability of your project. Our model is designed to maximize innovation in drug therapeutics and generate significant market value, positioning your venture for long-term success and impactful industry leadership..
• About the Role.
• We are seeking a motivated and experienced CRISPR Scientist to join our dynamic R&D team and drive the design, execution, and analysis of our gene editing projects. If you are passionate about translating innovative science into transformative medicine, we encourage you to apply..
• Design and execute experiments using various CRISPR-Cas systems (e.g., OPENCRISPR1, Cas9, Cas12a, Base Editors, Prime Editors) for gene editing in mammalian cells, including primary cells and immortalized cell lines. This scope of work is expected to include using machine learning platforms to screen, analyze, synthesize and test enzymes of the Cas and deaminase classes as well as nickase conversion..
• Develop and optimize methods for gRNA design, delivery (e.g., lipofectamine, lipid nanoparticles, electroporation), and assessment of editing efficiency and specificity using PCR and NGS technologies..
• Analyze and interpret complex data sets, including molecular biology assays (qPCR, Western Blot, ELISA), next-generation sequencing (NGS) data for on-target and off-target editing, and functional cell-based assays..
• Culture and manipulation of various cell lines (HEK-293, HeLa, iPSCs, and T cells), with a focus on validating utility of novel complexes to perform precise editing in cells..
• Troubleshoot experimental hurdles and contribute creative solutions to accelerate project timelines. This will include minimizing off-target and bystander editing by correct selection of PAMs and other critical sequences..
• Document experiments in electronic lab notebooks and present results clearly at internal meetings..
• Stay current with the latest scientific literature, technology advancements, and regulatory requirements pertaining to CRISPR and gene therapy..
• Collaborate effectively with interdisciplinary teams including technicians and scientists, in the immunology, cell biology, drug development and bioinformatics fields..
• Required.
• Ph.D. in Molecular Biology, Cell Biology, Genetics, Biochemistry, or a related field..
• Minimum of 2+ years of relevant post-doctoral or industry experience focused on gene editing techniques, specifically CRISPR technology. Experience in Base Editors and human T cells is desired..
• Deep expertise in mammalian cell culture techniques, including transfection and viral transduction..
• Proficiency in molecular biology techniques, including DNA/RNA isolation, PCR/qPCR, cloning, and gel electrophoresis..
• Demonstrated experience with assays used to quantify gene editing outcomes (e.g., T7 Endonuclease I assay, NGS library preparation and analysis)..
• Excellent written and verbal communication skills with the ability to present complex data effectively..
• Preferred.
• Industry experience in a Biotech or Pharmaceutical setting..
• Experience with non-Cas9 CRISPR systems (e.g., Base/Prime Editors, dCas9 fusions) is a strong plus..
• Familiarity with in vivo delivery methods and animal models..
• Experience with high-throughput screening and automation..
• Experience with CAR-T cell development.
• Experience with antiviral therapeutics..
• What We Offer.
• Competitive compensation and equity package in an early-stage, high-growth startup..
• The opportunity to make a significant impact on developing next-generation therapies..
• A collaborative, fast-paced, and intellectually stimulating culture..
• To Apply, please submit your CV and a cover letter detailing your relevant experience to [email protected] or Application Link: https://forms.gle/Ewgtmcgwuv6B5KJ66..

Experience:

5 years required

Skills:

Research, M&A, English

Job type:

Full-time

• Provides timely and accurate responses to internal and external medical inquiries about Pfizer products, and thereby acts as an essential medical contributor to the successful commercialization of products, activities and services of Pfizer.
• He/She is also required to manage Investigator Sponsored Research (ISR) and provide medical and scientific training, updates and communication to improve the internal and external capabilities when such a need arises.
• Coordinate among multiple categories and provide scientific input in working with cr ...
• Ensures promotional materials comply with local regulations and both ethically and scientifically sound so that our customers can make well-informed decisions and optimize the safe and effective use of our company s products.
• Contributes to the achievement of the company s strategic objectives and growth by participating in compliance initiatives and supporting the drive for clinical research activities. ML will also support the Cluster Medical Director in the leadership of the Medical team and may have line management responsibility for Field Medical team, interns and/or students as assigned.
• Geographic area covered by the role Vietnam/Thailand and Indochina Countries (Cambodia, Laos, Myanmar) MAIN REPONSIBILITIES COMMERCIAL SUPPORT Act as a core member of the Medical-Marketing team to provide medical inputs/advices to different medical functional groups and Marketing Department that support the products.
• Assist in defining product strategy as required.
• To ensure the Company maintains a high ethical and professional standard when dealing with the healthcare professionals and supporting other health care disciplines, and with consumers.
• Attend internal/ external meetings as required.
• To facilitate the interaction/partnership between Key Opinion Leader (KOLs), Academia, Clinicians, Researchers and Pfizer.
• Assist in therapeutic area and product training to cross-functional colleagues when required.
• Review company-sponsored program as needed to ensure its design complies with company SOPs, guidelines and local industry codes and regulations on ethics and patient confidentiality.
• Provide educational talks to HCPs or consumers if required.
• Act as a field-based medical contact to support medical-medical communications and KOL management.
• STAKEHOLDER ENGAGEMENT LEAD Define and develop an external stakeholder engagement plan that links to Thailand/Indochina PBG overall medical strategies.
• Develop strategic partnerships with key healthcare stakeholders; developing strategies aligned to customer needs in order to maintain a therapeutic leadership position.
• Act as the lead coordinator for GMG programs across all PBG Tas.
• Provide medical oversight on the Thailand/Indochina Patient Assistant Programs.
• FIELD MEDICAL Oversee Field Medical team to carry out field based medical (FBM) activities in response to the individual need of the respective TA and according to what has been described in Medical Plan in terms of FBM activities.
• To ensure that the messages delivered to the HCP are in compliance with international and local rules and regulations.
• To work on projects related to FBM as necessary.
• MEDICAL INFORMATION Provide a timely and accurate response to internal and external medical inquiries for Pfizer products.
• Organize, manage and maintain all medical inquiries/ responses/ files/ documents/ tracking logs electronically.
• Ensure all inquiries are responded within the set timeframes and are handled according to local regulatory requirements and Standard Operating Procedures (SOP) of Pfizer.
• REVIEW AND APPROVAL Review promotional materials as needed for accuracy and adherence to the relevant Pfizer policies, local industry codes and regulatory guidelines as required.
• Provide scientific and medical advice/ support to other internal stakeholders.
• TRAINING Provide disease(s), product(s) or basic pharmacology training to other relevant colleagues, as required, following liaison with the Training Department.
• To assist commercial and other relevant department to deliver training to external stakeholders upon request.
• Participate in both internal and external training/meetings recommended by supervisor to improve efficiency, competency and/or for future career development.
• INVESTIGATOR SPONSORED RESEARCH (ISR)/ REGIONAL OR LOCAL PFIZER SPONSORED TRIALS Discuss research concept with interested researcher, and communicate the nature and requirement of Pfizer s ISR.
• Facilitate submission of investigator sponsored pre-clinical and clinical proposals, and act as a liaison between Pfizer and ISR researcher.
• Facilitate research proposal screening and study placement, and follow up activities.
• Support Pfizer Regional or local sponsored trial (including post-marketing trial), which is not under the clinical research team, if applicable.
• SPECIAL PROJECTS (Specific to individual) May have responsibilities as Subject Matter Expert (SME) in the above functional areas. MANAGEMENT Support Cluster Medical Lead in the leadership of the Medical team.
• Provide input and support in the development of overall Medical Affairs strategies and objectives.
• Coaching team members, sharing expertise, inspiring others in the Medical Affairs team, promoting the team internally, and development of business strategies for the MA group.
• Assist the Medical Affairs colleagues in special projects, locally, regionally and internationally.
• SUPERVISION OF ASSOCIATES/STUDENTS/INTERNS (if applicable) Assist in the on boarding of new team members, students and interns.
• Oversee the performance management, professional and personal development of new team members, students and interns during their program or contract.
• ADDITIONAL ASSIGNMENT Emerging Market above country initiatives/projects as assigned.
• Assist in pipeline prioritization and product launch planning in country and/or Emerging Market.
• REQUIRED SKILLS Medical Degree (M.D., MBBS or equivalent) or Advanced degree in Medical Sciences e.g. Pharmacy, Life Sciences e.g. Pharmacy or related field.
• Good medical and scientific knowledge for the defined therapeutic area(s).
• Good understanding about the International and local pharmaceutical business and marketing practices.
• Good understanding of the local medical and regulatory environment.
• At least 5 years of experience in pharmaceutical industry in relevant medical, research & development functions.
• Proficiency in English and good computer usage.
• Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. Medical